Go beyond routine care1 More info with
a personalized path for cancer
prevention2 More info.
Genetic testing can help you identify potential risks of developing certain cancers.
- Includes FDA authorized reports.*Learn about Considerations and Limitations for Health Predispositions Reports, Carrier Status Reports and Genetic Health Risks
- Personalized recommendations.
- Privacy and protection of your data.
Year
Knowledge is power.
- Early action can lead to a healthier you.~40%of cancer deaths are linked to modifiable risk factors and may be preventable.3 More info
- Cancer can affect people of all ages.4/10people will develop cancer during their lifetime.4 More info
- Make more informed decisions about your care.#2Cancer is the second most common cause of death in the US.5 More info
Why genetic testing matters. We're here to help.
![Your genetics are associated with a typical likelihood](/_next/image/?url=%2F_next%2Fstatic%2Fmedia%2Fcancer-why-mb.155c29d2.png&w=750&q=75)
- Unlike routine cancer screening that may signal you already have a condition, genetic insights offer you information you can use for early intervention.
- Survival rates improve dramatically when cancer is diagnosed early.6 More info Depending on your genetics, standard screening and preventive steps may not be enough.
- Genetic insights can provide you with information on ways to take action and help you make more informed decisions.
We have three types of genetic reports to give you innovative insights for personalized next steps.
- Genetic Health Risk Reports*Learn about Considerations and Limitations for Health Predispositions Reports, Carrier Status Reports and Genetic Health RisksRare genetic variants that lead to an increased risk for certain types of cancers.
- Polygenic Risk Scores*Learn about Considerations and Limitations for Health Predispositions Reports, Carrier Status Reports and Genetic Health RisksCombinations of common genetic variants that impact the chances of developing common types of cancers.
- Pharmacogenetics Reports**Learn about Considerations and Limitations for Health Predispositions Reports, Carrier Status Reports and Genetic Health RisksGenetic variants that impact how your body may process certain cancer medications.
![A sample Heart Health report. Your genetics are associated with an increased likelihood.](/_next/image/?url=%2F_next%2Fstatic%2Fmedia%2Fcancer-report-mb.3b764257.png&w=750&q=75)
Genetic information for cancer and drug response.
Also included in your 23andMe+ Premium membership.
- BRCA1/BRCA2 (Selected Variants)
- Hereditary Prostate Cancer (HOXB13-Related)
- MUTYH-Associated Polyposis
- Breast Cancer PRS report (females only)
- Prostate Cancer PRS report (males only)
- Colorectal Cancer PRS report (certain ethnicities)
- Skin Cancer (Melanoma)
- Skin Cancer (Basal and Squamous Cell Carcinomas)
- DPYD Drug Metabolism
Tools for preventive action and better health over time.
Also included in your 23andMe+ Premium membership.
![](/_next/image/?url=%2F_next%2Fstatic%2Fmedia%2Fca-health-action-plan-mb.17f3e549.png&w=1920&q=75)
Health Action Plan
Your Health Action Plan allows you to opt in and receive personalized recommendations based on genetic and non-genetic data.
![](/_next/image/?url=%2F_next%2Fstatic%2Fmedia%2Fca-family-health-tree-mb.bf7f3114.png&w=1920&q=75)
Family Health History Tree
Opt in to easily input, track and download your family health history to share with your healthcare provider.
Find out what else you can learn from your DNA.
You’ll also receive 190+ reports with new insights and features added throughout the year.
- Type 2 Diabetes (Powered by 23andMe Research)
- Gestational Diabetes (Powered by 23andMe Research) (available for females only)
- High Blood Pressure (Powered by 23andMe Research)
- HDL Cholesterol (Powered by 23andMe Research)
- Triglycerides (Powered by 23andMe Research)
- Wellness Reports
- Genetic Weight
- Saturated Fat and Weight
- Late-Onset Alzheimer’s Disease Genetic Health Risk ReportOpt in to view your report results.
- Related Condition: Parkinson’s Disease Genetic Health Risk Report
- Depression (Powered by 23andMe Research)
- Anxiety (Powered by 23andMe Research)
- Panic Attacks (Powered by 23andMe Research)
- ADHD (Powered by 23andMe Research)
- Sleep Health Matters to Mental Health
- Insomnia (Powered by 23andMe Research)
- Obstructive Sleep Apnea (Powered by 23andMe Research)
- Restless Legs Syndrome (Powered by 23andMe Research)
- Wellness and Trait Reports
- Deep Sleep
- Sleep Movement
- Wake-Up Time
- Familial Hypercholesterolemia Genetic Health Risk Report
- Hereditary Amyloidosis (TTR-Related) Genetic Health Risk Report
- Atrial Fibrillation (Powered by 23andMe Research)
- Coronary Artery Disease (Powered by 23andMe Research)
- High Blood Pressure (Powered by 23andMe Research)
- Type 2 Diabetes (Powered by 23andMe Research)
- LDL Cholesterol (Powered by 23andMe Research)
- HDL Cholesterol (Powered by 23andMe Research)
- Triglycerides (Powered by 23andMe Research)
- Wellness Reports
- Genetic Weight
- Saturated Fat and Weight
- Pharmacogenetics Reports
- SLCO1B1 Drug Transport
- CYP2C19 Drug Metabolism
- Historical MatchesSM feature
- Advanced DNA Relative filters
- Access to up to 5000 DNA relatives
- Ancestry Detail Reports (48 reports)
Population-specific reports with maps covering 3000+ regions, offering a granular view of your ancestry, plus immersive educational content.
Reports included:
Americas (Caribbean, Mexico & Central America, Indigenous American, South America);
East Asia (Chinese, Chinese Dai, Filipino & Austronesian, Indonesian, Thai, Khmer & Myanma, Japanese, Korean, Manchurian & Mongolian, Siberian, Vietnamese);
Europe (Ashkenazi Jewish, British & Irish, Eastern European, Finnish, French & German, Greek & Balkan, Italian, Sardinian, Scandinavian, Spanish & Portuguese);
Oceania (Melanesian);
Central & South Asia (Bengali & Northeast Indian, Central Asian, Gujarati Patidar, Malayali Subgroup, Northern Indian & Pakistani, Southern Indian & Sri Lankan, Southern Indian Subgroup);
Sub-Saharan Africa (African Hunter-Gatherer, Angolan & Congolese, Ethiopian & Eritrean, Ghanaian, Liberian & Sierra Leonean, Nigerian, Senegambian & Guinean, Somali, Southern East African, Sudanese);
Western Asia & North Africa (Anatolian, Coptic Egyptian, Cypriot, Egyptian, Iranian, Caucasian & Mesopotamian, Levantine, North African, Peninsular Arab) - Family Tree
- Maternal Haplogroup
- Paternal Haplogroup
- Neanderthal Ancestry
- Ability to Match Musical Pitch
- Asparagus Odor Detection
- Back Hair (available for men only)
- Bald Spot (available for men only)
- Bitter Taste
- Bunions
- Cheek Dimples
- Cilantro Taste Aversion
- Cleft Chin
- Dandruff
- Earlobe Type
- Early Hair Loss (available for men only)
- Earwax Type
- Eye Color
- Fear of Heights
- Fear of Public Speaking
- Finger Length Ratio
- Flat Feet
- Freckles
- Hair Photobleaching (hair lightening from the sun)
- Hair Texture
- Hair Thickness
- Ice Cream Flavor Preference
- Light or Dark Hair
- Misophonia (hatred of the sound of chewing)
- Mosquito Bite Frequency
- Motion Sickness
- Newborn Hair
- Photic Sneeze Reflex
- Red Hair
- Skin Pigmentation
- Stretch Marks
- Sweet vs. Salty
- Toe Length Ratio
- Unibrow
- Wake-Up Time
- Widow's Peak
- Hereditary Prostate Cancer (HOXB13-Related)A DNA variant that increases risk for prostate cancer1 variant in the HOXB13 gene; relevant for European (especially Northern European) descent
- Anxiety
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing anxiety that interferes with daily lifeBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Asthma
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing a chronic lung condition characterized by shortness of breath, wheezing, and coughingBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Atrial Fibrillation
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for a type of irregular heartbeatBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Attention-Deficit/Hyperactivity Disorder (ADHD)
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of having ADHD, which can be associated with differences in attention, memory, and managing thoughts or behaviorsBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Bipolar Disorder
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of experiencing unusual shifts in mood, energy, activity, behavior, and sleep, beyond the normal ups and downs of lifeBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Breast Cancer (available for females only)
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing breast cancerBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Colorectal Cancer
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing cancer of the colon or rectumBased on a genetic model that includes customers' results for more than a thousand genetic markers; genetic result available for people with predominantly European and Hispanic/Latino ancestryThere is not enough data to create a genetic prediction that meets our scientific standards for people with other ancestries at this time. - Coronary Artery Disease
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for a type of heart diseaseBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Depression
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing persistent low mood, loss of interest, and other symptoms that interfere with daily lifeBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Diverticulitis
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for a condition that occurs when small pouches in the digestive tract become inflamedBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Eczema (Atopic Dermatitis)
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for a skin condition characterized by dry, discolored, and itchy skinBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Fibromyalgia
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing a condition characterized by chronic pain and tenderness throughout the bodyBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Gallstones
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing solid, pebble-like masses that form in the gallbladderBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Gestational Diabetes (available for females only)
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing a type of diabetes that occurs during pregnancyBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Glaucoma
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing an eye condition that can cause partial vision loss and blindnessBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Gout
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for a condition where one or more joints suddenly becomes painful and swollenBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Hashimoto’s Disease
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing an autoimmune condition in which the immune system causes damage to the thyroid glandBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - HDL Cholesterol
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing low levels of HDL (“good”) cholesterolBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - High Blood Pressure
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing high blood pressureBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Insomnia
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing a sleep disorder that causes chronic trouble with falling or staying asleepBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Irritable Bowel Syndrome
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing a chronic condition that impacts the large intestineBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Kidney Stones
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for solid, pebble-like masses that form in the kidneysBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - LDL Cholesterol
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing high levels of LDL ("bad") cholesterolBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Lupus
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing a chronic autoimmune condition that can affect many parts of the body, such as the joints, skin, lungs, kidneys, and heartBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Migraine
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of experiencing migraine headachesBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Nonalcoholic Fatty Liver Disease
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for a condition where fat builds up in the liverBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Obstructive Sleep Apnea
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for a condition where breathing stops and starts repeatedly during sleepBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Panic Attacks
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of experiencing episodes of intense fear that last a few minutes to an hourBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Polycystic Ovary Syndrome (PCOS) (available for females only)
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for a hormone disorder that affects femalesBased on a genetic model that includes customers' results for more than a thousand genetic markers; variants found in many ethnicities - Preeclampsia (available for females only)
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing persistent high blood pressure during pregnancyBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Prostate Cancer (available for males only)
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing cancer of the prostate, a male reproductive organBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Psoriasis
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing an autoimmune condition that can cause itchy, discolored patches to form on the skinBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Restless Legs Syndrome
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for a condition characterized by an uncontrollable urge to move one's legsBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Rosacea
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for a chronic skin condition that often causes redness or visible blood vessels in the faceBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Severe Acne
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for a skin condition characterized by many deep and painful types of pimples along with many whiteheads and blackheadsBased on a genetic model that includes customers' results for thousands of genetic markers; variants found in many ethnicities - Skin Cancer (Basal and Squamous Cell Carcinomas)
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing the two most common types of skin cancerBased on a genetic model that includes customers’ results for thousands of genetic markers; genetic result available for people of European, Hispanic/Latino, Northern African/Central & Western Asian, and Sub-Saharan African/African American descentOnly about 3 in 1000 23andMe research participants of East/Southeast Asian or South Asian descent report having been diagnosed with basal or squamous cell skin cancers. This means there is not enough data to create a genetic prediction that meets our scientific standards for people of these ethnicities at this time. - Skin Cancer (Melanoma)
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing a common type of skin cancerBased on a genetic model that includes customers’ results for more than a thousand genetic markers; genetic result available for people of European, Hispanic/Latino, and Northern African/Central & Western Asian descentOnly about 1 in 1000 23andMe research participants of East/Southeast Asian, South Asian, or Sub-Saharan African/African American descent report having been diagnosed with melanoma. This means there is not enough data to create a genetic prediction that meets our scientific standards for people of these ethnicities at this time. - Triglycerides
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood of developing high levels of triglycerides (a type of lipid)Based on a genetic model that includes customers' results for more than a thousand genetic markers; variants found in many ethnicities - Uterine Fibroids (available for females only)
(Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for a common type of non-cancerous growth in the uterusBased on a genetic model that includes customers' results for more than a thousand genetic markers; variants found in many ethnicities
- Type 2 Diabetes (Powered by 23andMe Research)Reports and features that are “Powered by 23andMe Research” are developed by 23andMe scientists using data and insights gathered from thousands of customers who have consented to participate in our research.Genetic likelihood for a disorder of blood sugar regulation1,000+ variants in many genes; variants found in many ethnicities
- Age-Related Macular DegenerationGenetic risk for a form of adult-onset vision loss2 variants in the ARMS2 and CFH genes; relevant for European descent
- Alpha-1 Antitrypsin DeficiencyGenetic risk for lung and liver disease2 variants in the SERPINA1 gene; relevant for European descent
- BRCA1/BRCA2 (Selected Variants)Genetic risk based on a limited set of variants for breast, ovarian, prostate and pancreatic cancer44 variants in the BRCA1 and BRCA2 genes; most relevant for Ashkenazi Jewish descent; does not include the majority of BRCA1/2 variants found in people of other ethnicities
- Celiac DiseaseGenetic risk for gluten-related autoimmune disorder2 variants near the HLA-DQB1 and HLA-DQA1 genes; relevant for European decent
- Chronic Kidney Disease (APOL1-Related)Genetic risk for a form of chronic kidney disease2 variants in the APOL1 gene; relevant for African descent
- Familial HypercholesterolemiaGenetic risk for very high cholesterol, which can increase the risk for heart disease24 variants in the LDLR and APOB genes; relevant for European, Lebanese, Old Order Amish descent
- G6PD DeficiencyGenetic risk for a form of anemia2 variants in the G6PD gene; relevant for African, Southern European, Kurdish Jewish, Middle Eastern, Central Asian, South Asian descent
- Hereditary Amyloidosis (TTR-Related)Genetic risk for a form of nerve and heart damage3 variants in the TTR gene; relevant for African American, West African, Portuguese, Brazilian, Northern Swedish, Japanese, Irish, British descent
- Hereditary Hemochromatosis (HFE‑Related)Genetic risk for iron overload2 variants in the HFE gene; relevant for European descent
- Hereditary ThrombophiliaGenetic risk for harmful blood clots2 variants in the F2 and F5 genes; relevant for European descent
- Late-Onset Alzheimer's DiseaseGenetic risk for a form of dementia1 variant in the APOE gene; variant found and studied in many ethnicities
- MUTYH-Associated PolyposisGenetic risk for a specific colorectal cancer syndrome2 variants in the MUTYH gene; relevant for Northern European descent
- Parkinson's DiseaseGenetic risk for a form of movement impairment2 variants in the LRRK2 and GBA genes; relevant for European, Ashkenazi Jewish, North African Berber descent
- ARSACS1 variant in the SACS gene; relevant for French Canadian descent
- Agenesis of the Corpus Callosum with Peripheral Neuropathy1 variant in the SLC12A6 gene; relevant for French Canadian descent
- Autosomal Recessive Polycystic Kidney Disease3 variants in the PKHD1 gene
- Beta Thalassemia and Related Hemoglobinopathies10 variants in the HBB gene; relevant for Sardinian, Cypriot, Italian/Sicilian, Greek descent
- Bloom Syndrome1 variant in the BLM gene; relevant for Ashkenazi Jewish descent
- Canavan Disease3 variants in the ASPA gene; relevant for Ashkenazi Jewish descent
- Congenital Disorder of Glycosylation Type 1a (PMM2-CDG)2 variants in the PMM2 gene; relevant for Ashkenazi Jewish, Danish descent
- Cystic Fibrosis29 variants in the CFTR gene; relevant for Ashkenazi Jewish, European, Hispanic/Latino descent
- D-Bifunctional Protein Deficiency2 variants in the HSD17B4 gene
- Dihydrolipoamide Dehydrogenase Deficiency1 variant in the DLD gene; relevant for Ashkenazi Jewish descent
- Familial Dysautonomia1 variant in the ELP1 gene; relevant for Ashkenazi Jewish descent
- Familial Hyperinsulinism (ABCC8-Related)3 variants in the ABCC8 gene; relevant for Ashkenazi Jewish descent
- Familial Mediterranean Fever7 variants in the MEFV gene; relevant for Arab, Armenian, Sephardic Jewish, Turkish descent
- Fanconi Anemia Group C3 variants in the FANCC gene; relevant for Ashkenazi Jewish descent
- GRACILE Syndrome1 variant in the BCS1L gene; relevant for Finnish descent
- Gaucher Disease Type 13 variants in the GBA gene; relevant for Ashkenazi Jewish descent
- Glycogen Storage Disease Type Ia1 variant in the G6PC gene; relevant for Ashkenazi Jewish descent
- Glycogen Storage Disease Type Ib2 variants in the SLC37A4 gene
- Hereditary Fructose Intolerance4 variants in the ALDOB gene; relevant for European descent
- Leigh Syndrome, French Canadian Type1 variant in the LRPPRC gene; relevant for French Canadian descent
- Limb-Girdle Muscular Dystrophy Type 2D1 variant in the SGCA gene
- Limb-Girdle Muscular Dystrophy Type 2E1 variant in the SGCB gene; relevant for Amish descent
- Limb-Girdle Muscular Dystrophy Type 2I1 variant in the FKRP gene
- MCAD Deficiency4 variants in the ACADM gene; relevant for European descent
- Maple Syrup Urine Disease Type 1B2 variants in the BCKDHB gene; relevant for Ashkenazi Jewish descent
- Mucolipidosis Type IV1 variant in the MCOLN1 gene; relevant for Ashkenazi Jewish descent
- Neuronal Ceroid Lipofuscinosis (CLN5-Related)1 variant in the CLN5 gene; relevant for Finnish descent
- Neuronal Ceroid Lipofuscinosis (PPT1-Related)3 variants in the PPT1 gene; relevant for Finnish descent
- Niemann-Pick Disease Type A3 variants in the SMPD1 gene; relevant for Ashkenazi Jewish descent
- Nijmegen Breakage Syndrome1 variant in the NBN gene
- Nonsyndromic Hearing Loss and Deafness, DFNB1 (GJB2-Related)8 variants in the GJB2 gene; relevant for many ethnicities, including Ashkenazi Jewish, East/Southeast Asian, European, and Ghanaian descent. May also be relevant for Hispanic/Latino, Northern African/Middle Eastern, and South Asian descent
- Pendred Syndrome and DFNB4 Hearing Loss (SLC26A4-Related)6 variants in the SLC26A4 gene
- Phenylketonuria and Related Disorders23 variants in the PAH gene; relevant for Irish, Northern European descent
- Pompe Disease5 variants in the GAA gene; relevant for African/African American descent; variants also common in European descent
- Primary Hyperoxaluria Type 21 variant in the GRHPR gene
- Pyruvate Kinase Deficiency1 variant in the PKLR gene
- Rhizomelic Chondrodysplasia Punctata Type 11 variant in the PEX7 gene
- Salla Disease1 variant in the SLC17A5 gene; relevant for Finnish, Swedish descent
- Severe Junctional Epidermolysis Bullosa (LAMB3-Related)3 variants in the LAMB3 gene
- Sickle Cell Anemia1 variant in the HBB gene; relevant for African, Middle Eastern, South Asian, Caribbean, Mediterranean, Central and South American descent
- Sjögren-Larsson Syndrome1 variant in the ALDH3A2 gene; relevant for Swedish descent
- Tay-Sachs Disease4 variants in the HEXA gene; relevant for Ashkenazi Jewish, Cajun descent
- Tyrosinemia Type I4 variants in the FAH gene; relevant for French Canadian, Finnish descent
- Usher Syndrome Type 1F1 variant in the PCDH15 gene; relevant for Ashkenazi Jewish descent
- Usher Syndrome Type 3A1 variant in the CLRN1 gene; relevant for Ashkenazi Jewish descent
- Zellweger Spectrum Disorder (PEX1-Related)1 variant in the PEX1 gene
- Cat Allergy
- Dog Allergy
- Nearsightedness
- Seasonal Allergies
- Alcohol Flush Reaction
- Caffeine Consumption
- Deep Sleep
- Genetic Weight
- Lactose Intolerance
- Muscle Composition
- Saturated Fat and Weight
- Sleep Movement
- CYP2C19 Drug Metabolism*DNA variants that influence how the body processes certain medications for depression, acid reflux, heart disease and other conditions3 variants in the CYP2C19 gene; variant found and studied in many ethnicities. Example medications: citalopram, omeprazole, clopidogrel
- Citalopram Medication InsightMedication Insight about how DNA variants may affect citalopram, a medication used to treat depression
- Clopidogrel Medication InsightMedication Insight about how DNA variants may affect clopidogrel, a medication used to reduce the risk for heart attack and stroke
- Citalopram Medication Insight
- DPYD Drug Metabolism*DNA variants that influence how the body processes certain cancer medications2 variants in the DPYD gene; variant found and studied in many ethnicities. Example medications: fluorouracil (5-FU), capecitabine
- SLCO1B1 Drug Transport*A DNA variant that influences how the body processes certain cholesterol-lowering medications1 variant in the SLCO1B1 gene; variant found and studied in many ethnicities
- Simvastatin Medication InsightMedication Insight about how DNA variants may affect simvastatin, a medication used to lower cholesterol levels and reduce the risk for heart attack, stroke, and other heart problems
- Simvastatin Medication Insight
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Add to cartImportant test infoFrequently Asked Questions
- What’s included in 23andMe+ Premium?
- The 23andMeplus Premium is an annual membership and includes everything from our Health plus Ancestry Service plus access to exclusive reports and features that can help you learn more about your heart health, how you process certain medications**Learn about Considerations and Limitations for Pharmacogenetics Reports, likelihood for having migraine, and more. You’ll also receive enhanced ancestry features. Together, these 23andMe reports and features provide a more in-depth dive into your health and ancestry.
- How much does it cost to join 23andMe+ Premium?
- A 23andMeplus Premium membership costs original price: $298 sale price: $229 for new customers (original price: $229 sale price: $160 for kit plus $69 for membership). Existing Ancestry Service customers can upgrade here. Existing Health + Ancestry customers can upgrade here. Membership for new and existing customers renews automatically at $69peryr.
- Can you cancel the 23andMe+ Premium?
- You can cancel your annual 23andMeplus Premium at any time from within your 23andMe Account Settings. Read more about canceling your membership here: https://www.23andme.com/about/tos/subscription/
- Is there a monthly fee for 23andMe?
- We offer two base DNA kits, Ancestry Service and Health plus Ancestry, which are a one-time fee. We also have an optional add-on to the Health plus Ancestry kit, 23andMeplus Premium, which is our annual membership service that offers exclusive access to new premium reports and features throughout the year.
3 Headline: What is Cancer?
Link: https://www.worldcancerday.org/what-cancer#:~:text=Key%20Cancer%20Facts,poor%20diet%20and%20physical%20inactivity
Source: World Cancer Day Organization of the Union for International Cancer Control
4 Headline: Cancer Statistics
Link: https://www.cancer.gov/about-cancer/understanding/statistics
Source: National Cancer Institute
5 Headline: Patterns in Cancer Incidence Among People Younger Than 50 Years in the US, 2010 to 2019
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10433086/
Source: National Library of Medicine
6 Headline: Stage at Diagnosis
Link: https://progressreport.cancer.gov/diagnosis/stage
Source: National Cancer Institute
*The 23andMe PGS test includes health predisposition and carrier status reports. Health predisposition reports include both reports that meet FDA requirements for genetic health risks and PRS reports which are based on a genetic model that includes data and insights from 23andMe consented research participants, and have not been reviewed by the FDA. The test uses qualitative genotyping to detect select clinically relevant variants in the genomic DNA of adults from saliva for the purpose of reporting and interpreting genetic health risks and reporting carrier status. It is not intended to diagnose any disease. Your ethnicity may affect the relevance of each report and how your genetic health risk results are interpreted. Each genetic health risk report describes if a person has variants associated with a higher risk of developing a disease, but does not describe a person’s overall risk of developing the disease. Each PRS report describes if a person has a certain likelihood of developing a condition, but does not describe a person’s overall likelihood. The test is not intended to tell you anything about your current state of health, or to be used to make medical decisions, including whether or not you should take a medication, how much of a medication you should take, or determine any treatment. Our carrier status reports can be used to determine carrier status, but cannot determine if you have two copies of any genetic variant. These carrier reports are not intended to tell you anything about your risk for developing a disease in the future, the health of your fetus, or your newborn child's risk of developing a particular disease later in life. For certain conditions, we provide a single report that includes information on both carrier status and genetic health risk. Warnings & Limitations: The 23andMe PGS Genetic Health Risk Report for BRCA1/BRCA2 (Selected Variants) is indicated for reporting of 44 variants in the BRCA1 and BRCA2 genes. The report describes if a person's genetic result is associated with an increased risk of developing breast cancer and ovarian cancer and may be associated with an increased risk for prostate cancer, pancreatic cancer, and potentially other cancers. The variants included in this report do not represent the majority of the BRCA1/BRCA2 variants in people of most ethnicities. The MUTYH-Associated Polyposis Genetic Health Risk Report is indicated for reporting the Y179C and G396D variants in the MUTYH gene and an increased risk for colorectal cancer. The two variants included in this report are most common in people of Northern European descent. The Hereditary Prostate Cancer (HOXB13-Related) Genetic Health Risk report is indicated for reporting the G84E variant in the HOXB13 gene. The report describes if a person has the G84E variant and if a male is at increased risk for prostate cancer. The variant included in this report is most common in people of European descent, especially in people of Northern European descent. These reports do not include variants in other genes linked to hereditary cancers and the absence of variants included in this report does not rule out the presence of other genetic variants that may impact cancer risk. These reports are for over-the-counter use by adults, and provide genetic information to inform discussions with a healthcare professional. The PGS test is not a substitute for visits to a healthcare professional for recommended screenings or appropriate follow-up. Results should be confirmed by an independent genetic test prescribed by your own healthcare provider before taking any medical action. For important information and limitations regarding genetic health risk reports, visit 23andme.com/test-info/.
**23andMe PGS Pharmacogenetics reports: The 23andMe test uses qualitative genotyping to detect 3 variants in the CYP2C19 gene, 2 variants in the DPYD gene and 1 variant in the SLCO1B1 gene in the genomic DNA of adults from saliva for the purpose of reporting and interpreting information about the processing of certain therapeutics to inform discussions with a healthcare professional. It does not describe if a person will or will not respond to a particular therapeutic. Our CYP2C19 Pharmacogenetics report provides certain information about variants associated with metabolism of some therapeutics and provides interpretive drug information regarding the potential effect of citalopram and clopidogrel therapy. Our SLCO1B1 Pharmacogenetics report provides certain information about variants associated with the processing of some therapeutics and provides interpretive drug information regarding the potential effect of simvastatin therapy. Our DPYD Pharmacogenetics report does not describe the association between detected variants and any specific therapeutic. Results for DPYD and certain CYP2C19 results should be confirmed by an independent genetic test prescribed by your own healthcare provider before taking any medical action. Warning: Test information should not be used to start, stop, or change any course of treatment and does not test for all possible variants that may affect metabolism or protein function. The PGS test is not a substitute for visits to a healthcare professional. Making changes to your current regimen can lead to harmful side effects or reduced intended benefits of your medication, therefore consult with your healthcare professional before taking any medical action. For important information and limitations regarding Pharmacogenetic reports, visit 23andme.com/test-info/pharmacogenetics/